Institute for Research on Cancer and Aging, Nice
Institute for Research on Cancer and Aging, Nice
Institute for Research on Cancer and Aging, Nice
Institute for Research on Cancer and Aging, Nice
Institute for Research on Cancer and Aging, Nice
Highlights & Outreach
Featured research
Stress Response and Oncogenesis
Dmitry BULAVIN, Research Director, DR1 Inserm
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Retrotransposons and genome plasticity
Gael CRISTOFARI, Research Director, DR2 Inserm
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Tumor-Stroma Crosstalk in Invasive Cancer
Cedric GAGGIOLI, Research Director, DR2 Inserm
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Epithelial homeostasis and tumorigenesis
Chloé FÉRAL, Research Director, DR2 Inserm
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Telomere Shortening in Cancer and Aging
Miguel GODINHO FERREIRA, Research Director, DR2 CNRS
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Carcinogenesis-related chronic active inflammation
Paul HOFMAN, Professor-Clinician, PU-PHCE
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Telomere, senescence and cancer
Eric GILSON, Director, Professor-Clinician, PU-PHCE
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Population genomics and complex traits
Gianni LITI, Research Director, DR1 CNRS
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Normal and pathological angiogenesis
Gilles PAGÈS, Research Director, DR1 Inserm
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Genetics of solid tumors
Florence PEDEUTOUR, Professor-Clinician, PU-PH1
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Genetics of mitochondrial diseases
Véronique PAQUIS-FLUCKLINGER, Professor-Clinician, PU-PHCE
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Stress Response, regeneration & longevity
Eric RÖTTINGER, Research Director, DR2 CNRS
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Transcription Specificity
Simona SACCANI, Research Director, DR2 Inserm
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Telomerase and adult stem cell homeostasis
Marina SHKRELI, Researcher, CRCN Inserm
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Molecular Hematology - Blood signals
Eirini TROMPOUKI, Research Director, DR2 Inserm
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Latest publications
PrevNext
The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging.
Ying Y, Hu X, Han P, Mendez-Bermudez A, Bauwens S, Eid R, Tan L, Pousse M, Giraud-Panis MJ, Lu Y, Gilson E, Ye J.
Nucleic Acids Res. 2022 Feb 28;50(4):2081-2095. doi: 10.1093/nar/gkac065. PMID: 35150283
Telomeres as a sentinel of population decline in the context of global warming.
Lemaître JF, Gaillard JM, Gilson E. Proc Natl Acad Sci U S A.
2022 Aug 30;119(35):e2211349119. doi: 10.1073/pnas.2211349119. Epub 2022 Aug 10. PMID: 35947638
Loss of atm in Zebrafish as a Model of Ataxia-Telangiectasia Syndrome.
Chen K, Wang P, Chen J, Ying Y, Chen Y, Gilson E, Lu Y, Ye J.
Biomedicines. 2022 Feb 7;10(2):392. doi: 10.3390/biomedicines10020392. PMID: 35203601
Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence.
Mendez-Bermudez A, Lototska L, Pousse M, Tessier F, Croce O, Latrick CM, Cherdyntseva V, Nassour J, Xiaohua J, Lu Y, Abbadie C, Gagos S, Ye J, Gilson
Nucleic Acids Res. 2022 Jul 22;50(13):7493-7510. doi: 10.1093/nar/gkac603. PMID: 35819196
Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells.
Cherfils-Vicini J, Gilson E.
EMBO Mol Med. 2019 Jul;11(7):e10845. doi: 10.15252/emmm.201910845. Epub 2019 Jun 13. PMID: 31273935
Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition.
Ghilain C, Gilson E, Giraud-Panis MJ.
Cells. 2021 Jul 11;10(7):1753. doi: 10.3390/cells10071753. PMID: 34359923
Long-lived post-mitotic cell aging: is a telomere clock at play?
Jacome Burbano MS, Gilson E.
Mech Ageing Dev. 2020 Jul;189:111256. doi: 10.1016/j.mad.2020.111256. Epub 2020 May 4. PMID: 32380018 Review.
Neutrophils: mediating TelOxidation and senescence.
Jacome Burbano MS, Cherfils-Vicini J, Gilson E.
EMBO J. 2021 May 3;40(9):e108164. doi: 10.15252/embj.2021108164. Epub 2021 Apr 20. PMID: 33880795
Heterochromatin replication goes hand in hand with telomere protection.
Mendez-Bermudez A, Giraud-Panis MJ, Ye J, Gilson E.
Nat Struct Mol Biol. 2020 Apr;27(4):313-318. doi: 10.1038/s41594-020-0400-1. Epub 2020 Mar 30. PMID: 32231287 Review.
The Power of Stress: The Telo-Hormesis Hypothesis.
Jacome Burbano MS, Gilson E.
Cells. 2021 May 11;10(5):1156. doi: 10.3390/cells10051156.
Chapter 30: Phylum Hemichordata
Röttinger E & Osborn K J
Atlas of Marine Invertebrate Larvae, in press.
Editors: Young Craig M., Sewell Mary A., Boyle Michael J. Academic Press, Elsevier, Cambridge (USA)
PMID: XXX
Evolutionary conserved Mechano-Biochemical Marine Stimulation of Inversion, Gastrulation and Endomesoderm formation in multicellular Eukariota
Nguyen NM, Merle T, Broders F, Brunet A-C, Battistella A, Linnea Land E-B, Sarron F, Jha A, Gennisson J-L, Röttinger E, Fernandez-Sanchez ME & Farge E.
Frontiers in Cell and Developmental Biology, 10: 992371
PMID: 9754125