Dans le cadre des Contrats de Plan Etat-Région, PEMED-PCV reçoit le soutien des Fonds FEDER de l’Union européenne, de l’Etat, de la Région Sud Provence-Alpes-Côte d’Azur, du Département des Alpes-Maritimes pour le CPER PEMED-PCV
Since its inception in 2012, IRCAN has been dedicated to creating and operating cutting-edge Technical Core Facilities designed to enhance and support groundbreaking research projects and educational initiatives. These facilities, pivotal to IRCAN’s goal of fostering high-caliber scientific research, welcome both internal and external research groups from academic and industrial sectors in accordance with their GIS IBiSA certification. They are managed by highly skilled engineer and researcher staff linked with local and national networks of expertise’s.
These platforms offer technical and scientific expertise and services, from original pre-clinical models (marine models, spheroids, etc.) to high-throughput screening and statistical analysis (flow/imaging cytometry and image analysis), high-resolution and multi-dimensional imaging (confocal, spectral, evanescent wave and Airyscan imaging).
The development of these Technical Core Facilities and Common Services has been made possible through the committed efforts of IRCAN staff and substantial contributions from the Université Côte d’Azur, Inserm, CNRS, ARC, GIS IBiSA, Cancéropôle PACA, the Ville de Nice, the Department 06, the Region Sud, and the European Commission (FEDER Program).
ANTIAGE and 3D-Hub-S are certified by the GIS IBiSA since 2024. PICMI/PICMI AFM and CYTOMED are partners of the “Microscopie Imagerie Cytometrie Azur” multi-site platform certified by the GIS IBiSA since 2010, which gathers resources and skills from 8 academic partners in the Côte.
The 3D-Hub-S platform is expert in the study of the tumour microenvironment: interactions with stromal, endothelial and immune cells, fibroblasts, adipocytes and pericytes within a complex extracellular matrix. Its aim is to provide expertise and models in the field of multicellular spheroids and tumoroids that faithfully reproduce the complex ecosystem of solid tumours, and to contribute to the development and validation of anti-tumour therapies.
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The IRCAN Marine Invertebrate Facility for (anti) Aging Research (ANTIAGE) provides access to innovative marine invertebrate research models (sea anemone and corals) to study stress response, regeneration and aging/longevity. Using state-of-the-art aquarium and experimentation systems combined with a longstanding, solid and
internationnaly recongized expertise, this platform is the only one of its kind in France located within a Medical School.
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IRCAN Genomics Core Facility, GenoMed, is dedicated to the analysis of genetic variation, gene expression and its regulation. It provides knowledge and access to cutting-edge, medium-to-high throughput tools and technologies. It is open to all members of IRCAN, as well as to external academic or non-academic members of the scientific community.
GenoMed, the IRCAN genomics platform is a shared core facility dedicated to the analysis of genetic variation, gene expression and its regulation. It is open to all fundamental and applied research teams, whether academic or private. It provides expertise, equipments and services to identify and quantify DNA or RNA species, variations and modifications, at the level of the entire genome or at specific loci. Genomed is equipped for short- and long-read sequencing (Illumina, Oxford Nanopore Technologies) and library preparation, quality control and hit validation (e.g., DNA fragmentation, RNA and DNA microfluidic electrophoresis, quantitative PCR, droplet digital PCR).
Pasteur-IRCAN Molecular and Cellular Imaging Platform
PICMI combines expertise in light microscopy and 2D/3D image analysis for the life sciences with highly specialized equipment and software to help characterize cell and tissue morphologies and phenotypes.
IRCAN’s biological atomic force microscopy facility (AFM-PICMI) is the only one to date providing the Côte d’Azur scientific community with atomic force microscopy for life sciences. It offers a unique expertise in optimizing and developing applications for the nano-characterization (topography and nanomechanics) of biological samples, ranging from cell and tissue to single molecule.
The molecular analysis service provides equipment access and training for biochemical and molecular biology analyses essential to study cancer and ageing at the molecular, cellular or tissular levels. It includes molecular imager for immunoblot, quantitative real-time PCR machines, plate readers for absorbance, fluorescence and luminescence.
Histology facility
The Histology facility, located within PMED, provides all the necessary equipment to carry out every step of tissue preparation for staining and labeling. The facility is equipped to perform routine histological techniques on fixed, frozen, recorded, or fresh samples. It’s mission is to provide technical services, advice, and training in histology.
These platforms are coordinated and managed by:
Frédéric BRAU
Operation director of PEMED
Tel: +33(0)4 89 15 37 34
Email: frederic.brau@cnrs.fr
Nadine FEDOU
Administration & finance
Tel: +33 (0)4 89 15 36 68
Email: nadine.fedou@univ-cotedazur.fr
Find out what projects IRCAN researchers are working on at the moment!
Find out about our platforms and services that drive our research.
IRCAN has a diverse research teams, tackling a wide range and resolution of topics in ageing and cancer.
