Welcome to the IRCAN Patents page, where innovation meets industry. Our groundbreaking research does not just push scientific boundaries—it also leads to tangible, patentable innovations that serve as foundational elements for new industry standards and start-up ventures.
The journey from lab discovery to patented technology is a hallmark of IRCAN’s mission. Each patent represents a step forward in our understanding and ability to treat complex diseases.
Our commitment to pioneering research is evident in the numerous patents that have originated from IRCAN. These patents are a testament to our leading-edge scientific inquiry and our dedication to advancing the field of cancer and aging. By securing intellectual property rights for our discoveries, we ensure that our innovations have the protection and support needed to move from concept to commercialisation.
Explore our patents here
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METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OSTEOARTHRITIS
Application: EP2023079262W·2023-10-20 Inventors: CHERFILS-VICINI JULIEN [FR]; GILSON ERIC [FR]; JORGENSEN CHRISTIAN [FR]; BRONDELLO JEAN-MARC [FR]; PERS YVES-MARIE [FR]; FISSOUN CHRISTINA [FR] SUMMARY OF THE INVENTION: The present invention relates to methods and pharmaceutical compositions for the treatment of osteoarthritis. In particular, the present invention is defined by the claims.
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METHOD OF GENERATING iPSC LINES WITH TOTIPOTENT PROPERTIES
EP2023059341W·2023-04-07 Inventors : BULAVIN DMITRY [FR]; GRIGORASH BOGDAN [FR] SUMMARY OF THE INVENTION In the experimental part which follows, the inventors, using genetic, chemical and mechanical approaches to manipulate senescent cells, showed that removal of p16Hi9h cells results in the 4 factor-induced reprogramming into embryonic stem cells with totipotent potential. Established induced stem cells with…
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METHODS AND COMPOSITIONS FOR TREATING CELL SENESCENCE ACCUMULATION RELATED DISEASE
Application: EP2022060713W·2022-04-22 Inventors: CHERFILS JULIEN [FR]; GILSON ERIC [FR]; ILTIS CHARLÈNE [FR] SUMMARY OF THE INVENTION: The invention relates to methods and compositions for use in the prevention or treatment cell senescence accumulation related disease in a subject in need thereof. The present invention also relates to diagnosis or prognosis methods of cell senescence accumulation…
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COMPOUNDS FOR TREATING A DISEASE ASSOCIATED WITH MACROPHAGE SENESCENCE
International PCT No. PCT/EP2021/082221, 18 november 2021 Inventors: Bulavin DV, Triana-Martinex F SUMMARY OF THE INVENTION The inventors have surprisingly discovered that the majority of macrophages in an old animal carry the markers of senescence. They speculate that an ageing-induced senescence is an important contributor to macrophage hyper-reactivity in COVID-19 patients. Thus, lowering the level…
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METHODS FOR PREDICTING THE RESPONSE TO TREATMENT AND FOR TREATING CANCER
Application : EP2015054593W·2015-03-05 Inventors : Cherfils-Vicini J, Fridman WH, and Cremer I SUMMARY OF THE INVENTION The inventors have discovered that a high expression of TLR7 confers poor overall survival and impacts response to treatment in patients treated with neo-adjuvant chemotherapy, making TLR7 a strong prognostic marker. In addition, the inventors have shown that TLR7…
