Thesis Defense : Quynh-Huong LAI « Coevolution and functional diversification of the TRF2-Apollo interaction in jawed vertebrates »
Thesis director : Marie-Josèphe GIRAUD PANIS Abstract : Telomere repeat-binding factor 2 (TRF2) recruits the 5′ exonuclease Apollo through its TRFH domain, a step required for telomere-end processing and for the formation of the protective 3′ G-overhang. However, the evolutionary conservation and functional variation of this interaction across vertebrates remain poorly understood. Here, we combined […]