Mis en avant
External Seminar : « A garden of forking paths: branching, switching and reversal in meiotic recombination » – Michael Lichten
Abstract: Meiotic recombination involves repair of double strand DNA breaks by homologous recombination to form crossovers and noncrossovers. Current models suggest that different mechanisms form these two products: noncrossovers by synthesis-dependent strand annealing; COs by double Holliday junction formation and resolution. In testing these predictions, we found evidence for remarkable dynamism during meiotic DSB repair. […]